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    Combo-pilling is the newest fad or also the newest to come under scrutiny and for that reason it is just more publicly known lately, comb-pilling to lose weight has been around since the eighties. The biggest reason that using a combination of pills is starting to become popular could be the fact that by right now there aren't any long term prescription diet pills that have been approved by the FDA aside from orlistat. The truly disturbing part is doctors are prescribing these combinations of medications even though some of the combinations are already rejected or have yet to be approved by the FDA.

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    The FDA also warned that Contrave can raise blood pressure and heartbeat and must not used in patients with uncontrolled high blood pressure levels, along with by a person with heart-related and cerebrovascular (circulatory dysfunction impacting mental performance) disease. Patients using a history of cardiac event or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded from your clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, considering that the compound includes bupropion, Contrave comes with a boxed warning to alert medical professionals and patients to the increased risk of suicidal thoughts and behaviors connected with antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for stop smoking.

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